Thu, 21 Aug 2008 17:27:18 BST CiteULike: nelmor Romo http://www.citeulike.org/user/nelmor/author/Romo CiteULike.org en-gb Copyright © 2004-2008 citeulike.org http://www.citeulike.org/user/nelmor/article/1809995 <i>Proceedings of the National Academy of Sciences (16 October 2007), 0707961104.</i><br /><br />Depending on environmental demands, a decision based on a sensory evaluation may be either immediately reported or postponed for later report. If postponed, the decision must be held in memory. But what exactly is stored by the underlying memory circuits, the final decision itself or the sensory information that led to it? Here, we report that, during a postponed decision report period, the activity of medial premotor cortex neurons encodes both the result of the sensory evaluation that corresponds to the monkey's possible choices and past sensory information on which the decision is based. These responses could switch back and forth with remarkable flexibility across the postponed decision report period. Moreover, these responses covaried with the animal's decision report. We propose that maintaining in working memory the original stimulus information on which the decision is based could serve to continuously update the postponed decision report in this task. 10.1073/pnas.0707961104 Neural correlates of a postponed decision report Luis Lemus Adrian Hernandez Rogelio Luna Antonio Zainos Veronica Nacher Ranulfo Romo doi:10.1073/pnas.0707961104 Proceedings of the National Academy of Sciences (16 October 2007), 0707961104. 2007-10-23T09:32:44-00:00 2007 Proceedings of the National Academy of Sciences 0707961104 analysis cortex decision memory monkeys