Fri, 25 Jul 2008 15:34:29 BST CiteULike: msuarezdiez opinion http://www.citeulike.org/user/msuarezdiez/tag/opinion CiteULike.org en-gb Copyright © 2004-2008 citeulike.org http://www.citeulike.org/user/msuarezdiez/article/1135436 <i>Curr Opin Chem Biol, Vol. 9, No. 2. (April 2005), pp. 195-201.</i><br /><br />Catalytic promiscuity - the ability of a single active site to catalyse more than one chemical transformation - has a natural role in evolution and occasionally in biosynthesis of secondary metabolites. Catalytic promiscuity is more widespread than often recognized. Recent success in adding and enhancing such catalytic activities by protein engineering suggests new potential applications in enzyme-catalyzed organic synthesis. Enhancing catalytic promiscuity for biocatalysis. RJ Kazlauskas doi:10.1016/j.cbpa.2005.02.008 Curr Opin Chem Biol, Vol. 9, No. 2. (April 2005), pp. 195-201. 2007-03-02T07:55:32-00:00 2005 Curr Opin Chem Biol 1367-5931 9 2 195 201 enzyme_design opinion