Thu, 21 Aug 2008 15:20:03 BST CiteULike: cactus Sweeney http://www.citeulike.org/user/cactus/author/Sweeney CiteULike.org en-gb Copyright © 2004-2008 citeulike.org http://www.citeulike.org/user/cactus/article/2029894 <i>The EMBO Journal, Vol. aop, No. current. (29 November 2007)</i> The post-rigor structure of myosin VI and implications for the recovery stroke Julie Menetrey Paola Llinas Jerome Cicolari Gaelle Squires Xiaoyan Liu Anna Li Lee Sweeney Anne Houdusse doi:10.1038/sj.emboj.7601937 The EMBO Journal, Vol. aop, No. current. (29 November 2007) 2007-11-30T17:38:26-00:00 2007 The EMBO Journal 0261-4189 aop current Nature Publishing Group motor myosin xray-crystal-structure http://www.citeulike.org/user/cactus/article/1302495 <i>The EMBO Journal, Vol. aop, No. current. (17 May 2007)</i> How myosin VI coordinates its heads during processive movement Lee Sweeney Hyokeun Park Alan Zong Zhaohui Yang Paul Selvin Steven Rosenfeld doi:10.1038/sj.emboj.7601720 The EMBO Journal, Vol. aop, No. current. (17 May 2007) 2007-05-17T15:09:10-00:00 2007 The EMBO Journal 0261-4189 aop current Nature Publishing Group binding experiment motor myosin strain http://www.citeulike.org/user/cactus/article/2234123 <i>Cell, Vol. 131, No. 2. (19 October 2007), pp. 300-308.</i><br /><br />Summary Due to a unique addition to the lever arm-positioning region (converter), class VI myosins move in the opposite direction (toward the minus-end of actin filaments) compared to other characterized myosin classes. However, the large size of the myosin VI lever arm swing (powerstroke) cannot be explained by our current view of the structural transitions that occur within the myosin motor. We have solved the crystal structure of a fragment of the myosin VI motor in the structural state that represents the starting point for movement on actin; the pre-powerstroke state. Unexpectedly, the converter itself rearranges to achieve a conformation that has not been seen for other myosins. This results in a much larger powerstroke than is achievable without the converter rearrangement. Moreover, it provides a new mechanism that could be exploited to increase the powerstroke of yet to be characterized plus-end-directed myosin classes. The Structural Basis for the Large Powerstroke of Myosin VI Julie Menetrey Paola Llinas Monalisa Mukherjea Lee Sweeney Anne Houdusse doi:10.1016/j.cell.2007.08.027 Cell, Vol. 131, No. 2. (19 October 2007), pp. 300-308. 2008-01-15T08:33:28-00:00 2007 Cell 131 2 300 308 motor myosin xray-crystal-structure http://www.citeulike.org/user/cactus/article/78144 <i>Philosophical Transactions: Biological Sciences, Vol. 359, No. 1452., 1829.</i> The motor mechanism of myosin V: insights for muscle contraction Lee Sweeney Anne Houdusse doi:10.1098/rstb.2004.1576 Philosophical Transactions: Biological Sciences, Vol. 359, No. 1452., 1829. 2005-01-14T07:34:49-00:00 Philosophical Transactions: Biological Sciences 0962-8436 359 1452 1829 Royal Society motor myosin review