Sat, 05 Jul 2008 03:30:51 BST CiteULike: brembs Reyes http://www.citeulike.org/user/brembs/author/Reyes CiteULike.org en-gb Copyright © 2004-2008 citeulike.org http://www.citeulike.org/user/brembs/article/877189 <i>Science, Vol. 296, No. 5573. (31 May 2002), pp. 1706-1709.</i><br /><br />Operant conditioning is a form of associative learning through which an animal learns about the consequences of its behavior. Here, we report an appetitive operant conditioning procedure in Aplysia that induces long-term memory. Biophysical changes that accompanied the memory were found in an identified neuron (cell B51) that is considered critical for the expression of behavior that was rewarded. Similar cellular changes in B51 were produced by contingent reinforcement of B51 with dopamine in a single-cell analog of the operant procedure. These findings allow for the detailed analysis of the cellular and molecular processes underlying operant conditioning. Operant reward learning in Aplysia: neuronal correlates and mechanisms. B Brembs FD Lorenzetti FD Reyes DA Baxter JH Byrne doi:10.1126/science.1069434 Science, Vol. 296, No. 5573. (31 May 2002), pp. 1706-1709. 2006-09-29T06:48:42-00:00 2002 Science 1095-9203 296 5573 1706 1709 aplysia conditioning learning memory neurobiology neuroscience operant physiology slug snail