inbetweener profile

Recent Activity

• 22:32: posted Morphologic studies of motor units in normal human muscles.

• 18:29: posted Intranuclear inclusions and neuritic aggregates in transgenic mice expressing a mutant N-terminal fragment of huntingtin [published erratum appears in Hum Mol Genet 1999 May;8(5):943]
• 18:12: posted Regulation of Intracellular Accumulation of Mutant Huntingtin by Beclin 1
• 17:54: posted Absence of behavioral abnormalities and neurodegeneration in vivo despite widespread neuronal huntingtin inclusions.
• 17:30: posted Aggregate-prone proteins with polyglutamine and polyalanine expansions are degraded by autophagy.
• 17:30: posted Inhibition of mTOR induces autophagy and reduces toxicity of polyglutamine expansions in fly and mouse models of Huntington disease.
• 17:19: posted Huntingtons disease: degradation of mutant huntingtin by autophagy
• 17:18: posted Huntingtin Expression Stimulates Endosomal-Lysosomal Activity, Endosome Tubulation, and Autophagy
• 17:12: posted Huntingtin localization in brains of normal and Huntington's disease patients
• 16:06: posted Exon 1 of the HD gene with an expanded CAG repeat is sufficient to cause a progressive neurological phenotype in transgenic mice.