A neural mechanism for working and recognition memory in inferior temporal cortex.

by: EK Miller, L Li, R Desimone

Science, Vol. 254, No. 5036. (29 November 1991), pp. 1377-1379.

View FullText article

DOI, HighWire, Pubmed, Hubmed

Reviews [Write a review of this article]

There are no reviews of this article

Find related articles from these CiteULike users

AbelThorne, Neuroscience (group), Computational-Neurobiology (group), Inserm-U455 (group), bhamcnil

Find related articles with these CiteULike tags

habituation, neuroscience, no-tag, working_memory

Abstract

Inferior temporal (IT) cortex is critical for visual memory, but it is not known how IT neurons retain memories while new information is streaming into the visual system. Single neurons were therefore recorded from IT cortex of two rhesus monkeys performing tasks that required them to hold items in memory while concurrently viewing other items. The neuronal response to an incoming visual stimulus was attenuated if it matched a stimulus actively held in working memory, even when several other stimuli intervened. The neuronal response to novel stimuli declined as the stimuli became familiar to the animal. IT neurons appear to function as adaptive mnemonic "filters" that preferentially pass information about new, unexpected, or not recently seen stimuli.

@article{citeulike:1076465, abstract = {Inferior temporal (IT) cortex is critical for visual memory, but it is not known how IT neurons retain memories while new information is streaming into the visual system. Single neurons were therefore recorded from IT cortex of two rhesus monkeys performing tasks that required them to hold items in memory while concurrently viewing other items. The neuronal response to an incoming visual stimulus was attenuated if it matched a stimulus actively held in working memory, even when several other stimuli intervened. The neuronal response to novel stimuli declined as the stimuli became familiar to the animal. IT neurons appear to function as adaptive mnemonic "filters" that preferentially pass information about new, unexpected, or not recently seen stimuli.}, address = {Laboratory of Neuropsychology, National Institute of Mental Health, Bethesda, MD 20892.}, author = {Miller, E. K. and Li, L. and Desimone, R. }, citeulike-article-id = {1076465}, doi = {http://dx.doi.org/10.1126/science.1962197}, issn = {0036-8075}, journal = {Science}, keywords = {habituation, neuroscience, working\_memory}, month = {November}, number = {5036}, pages = {1377--1379}, posted-at = {2007-01-30 15:12:40}, priority = {2}, title = {A neural mechanism for working and recognition memory in inferior temporal cortex.}, url = {http://dx.doi.org/10.1126/science.1962197}, volume = {254}, year = {1991} }

RIS record

TY - JOUR ID - citeulike:1076465 L3 - citeulike-article-id:1076465 TI - A neural mechanism for working and recognition memory in inferior temporal cortex. JF - Science VL - 254 IS - 5036 SP - 1377 EP - 1379 AD - Laboratory of Neuropsychology, National Institute of Mental Health, Bethesda, MD 20892. SN - 0036-8075 N2 - Inferior temporal (IT) cortex is critical for visual memory, but it is not known how IT neurons retain memories while new information is streaming into the visual system. Single neurons were therefore recorded from IT cortex of two rhesus monkeys performing tasks that required them to hold items in memory while concurrently viewing other items. The neuronal response to an incoming visual stimulus was attenuated if it matched a stimulus actively held in working memory, even when several other stimuli intervened. The neuronal response to novel stimuli declined as the stimuli became familiar to the animal. IT neurons appear to function as adaptive mnemonic "filters" that preferentially pass information about new, unexpected, or not recently seen stimuli. KW - habituation KW - neuroscience KW - working_memory AU - Miller, EK AU - Li, L AU - Desimone, R PY - 1991/11/29/ UR - http://dx.doi.org/10.1126/science.1962197 ER -

RIS BibTeX