The human genome browser at UCSC

@article{Kent_etal02, abstract = {As vertebrate genome sequences near completion and research refocuses to their analysis, the issue of effective genome annotation display becomes critical. A mature web tool for rapid and reliable display of any requested portion of the genome at any scale, together with several dozen aligned annotation tracks, is provided at http://genome.ucsc.edu. This browser displays assembly contigs and gaps, mRNA and expressed sequence tag alignments, multiple gene predictions, cross-species homologies, single nucleotide polymorphisms, sequence-tagged sites, radiation hybrid data, transposon repeats, and more as a stack of coregistered tracks. Text and sequence-based searches provide quick and precise access to any region of specific interest. Secondary links from individual features lead to sequence details and supplementary off-site databases. One-half of the annotation tracks are computed at the University of California, Santa Cruz from publicly available sequence data; collaborators worldwide provide the rest. Users can stably add their own custom tracks to the browser for educational or research purposes. The conceptual and technical framework of the browser, its underlying MYSQL database, and overall use are described. The web site currently serves over 50,000 pages per day to over 3000 different users.}, address = {Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Cruz, CA 95064, USA. kent@biology.ucsc.edu}, author = {Kent, W. J. and Sugnet, C. W. and Furey, T. S. and Roskin, K. M. and Pringle, T. H. and Zahler, A. M. and Haussler, D. }, citeulike-article-id = {922643}, journal = {Genome Res}, keywords = {1001, 20020702, acid, california, database, databases, expression, gene, genes, genetic, genome, govt, homology, human, humans, management, messenger, non-phs, non-us, nucleic, phs, research, rna, sequence, software, structural, support, systems, universitiestrends, us}, month = {Jun}, number = {6}, pages = {996--1006}, posted-at = {2006-11-02 10:08:38}, priority = {2}, title = {The human genome browser at UCSC}, volume = {12}, year = {2002} }

TY - JOUR ID - Kent_etal02 L3 - citeulike-article-id:922643 TI - The human genome browser at UCSC JF - Genome Res VL - 12 IS - 6 SP - 996 EP - 1006 AD - Department of Molecular, Cellular, and Developmental Biology, University of California, Santa Cruz, CA 95064, USA. kent@biology.ucsc.edu N2 - As vertebrate genome sequences near completion and research refocuses to their analysis, the issue of effective genome annotation display becomes critical. A mature web tool for rapid and reliable display of any requested portion of the genome at any scale, together with several dozen aligned annotation tracks, is provided at http://genome.ucsc.edu. This browser displays assembly contigs and gaps, mRNA and expressed sequence tag alignments, multiple gene predictions, cross-species homologies, single nucleotide polymorphisms, sequence-tagged sites, radiation hybrid data, transposon repeats, and more as a stack of coregistered tracks. Text and sequence-based searches provide quick and precise access to any region of specific interest. Secondary links from individual features lead to sequence details and supplementary off-site databases. One-half of the annotation tracks are computed at the University of California, Santa Cruz from publicly available sequence data; collaborators worldwide provide the rest. Users can stably add their own custom tracks to the browser for educational or research purposes. The conceptual and technical framework of the browser, its underlying MYSQL database, and overall use are described. The web site currently serves over 50,000 pages per day to over 3000 different users. KW - 1001 KW - 20020702 KW - acid KW - california KW - database KW - databases KW - expression KW - gene KW - genes KW - genetic KW - genome KW - govt KW - homology KW - human KW - humans KW - management KW - messenger KW - non-phs KW - non-us KW - nucleic KW - phs KW - research KW - rna KW - sequence KW - software KW - structural KW - support KW - systems KW - universitiestrends KW - us AU - Kent, WJ AU - Sugnet, CW AU - Furey, TS AU - Roskin, KM AU - Pringle, TH AU - Zahler, AM AU - Haussler, D PY - 2002/Jun// ER -