CiteULike is a free online bibliography manager. Register
and you can start organising your references online.
Structural intermediates in microtubule assembly and disassembly: how and why?Current Opinion in Cell Biology, Vol. 18, No. 2. (April 2006), pp. 179-184.
|
Reviews
[Write a review of this article]
There are no reviews of this article
Find related articles from these CiteULike users Find related articles with these CiteULike tags AbstractMicrotubules are cytoskeletal polymers made of repeating [alpha][beta]-tubulin heterodimers that play essential roles in all eukaryotic cells. The complex dynamic behavior of microtubules, which is ultimately due to the tubulin subunit structure and its intrinsic GTPase activity, is key to the functions of these ubiquitous polymers. Microtubule assembly and disassembly do not take place by simple helical growth and shrinkage via individual subunits, but rather involve transient polymer intermediates, distinct from the microtubule, without parallel in other biological self-assembly systems. The discovery of these intermediates a decade ago has been followed recently by quantitative descriptions of their structure and their relationship to nucleotide state.
BibTeX record RIS record0001 0400 0500 0900 0901 0-useful 1000 1001 10331280 10396181 10877944 10886383 11009408 1101 11133193 11268209 11301139 11312593 12097345 12116654 12237351 12237393 12376687 12554461 12824072 14000 14530139 14668120 14766971 15145807 15184666 15205054 15205059 15374874 15475341 15519979 15522808 15539448 15546982 15608167 15615680 15653393 15654107 15814341 15865993 15921052 15928008 15963888 16012113 16040277 16151187 16397468 16572163 16genetics 16s 1915 19901025 19920301 19950210 19950421 19960101 19960401 19970121 19970425 19970701 19970801 19971010 19980228 19980321 19980605 19980731 19980919 19990209 19990311 19990709 19990911 19991111 19991230 19th 1genetics 2 20 20000226 20000508 20000608 20000617 20000718 20000919 20010228 20010303 20010307 20010327 20010522 20010629 20010728 20010803 20020105 20020131 20020205 20020228 20020312 20020427 20020531 20020702 20020820 20020829 20020907 20021003 20021019 20021031 20021126 20021228 20030315 20030318 20030328 20030412 20030417 20030506 20030528 20030605 20030802 20030812 20030819 20030820 20030822 20030828 20031010 20031206 20031210 20040107 20040121 20040203 20040221 20040310 20040318 20040513 20040518 20040527 20040616 20040621 20040721 20040724 20040728 20040818 20040821 20040824 20040826 20040924 20041002 20041013 20041216 20041222 20041223 20041230 20050120 20050208 20050212 20050317 20050325 20050326 20050331 20050409 20050416 20050505 20050511 20050601 20050610 20050618 20050623 20050628 20050701 20050713 20050719 20050729 20050810 20050816 20050820 20050913 20050915 20051019 20051220 2007 20genetics 20th 21 21-22 21genetics 22 22genetics 2genetics 2metabolismpharmacology 3 414315 5 5s 70-gene 76-gene 7764198 7genetics 8121278 8728393 8882504 9169434 9299221 9391098 aaa aberration abeta1-42 a-bgenetics acetylation acetyltransferases acetyltransferasesgeneticsmetabolism acid acidgenetics acidic acids acidsmetabolism acidspharmacology active active_site activity actkey acyclovir adaptation adaptive_algorithms adaptive_computation adaptive_evolution adatptive_computation adenosine adenosinemetabolism adenosinetriphosphatasegenetics adenosinetriphosphatasemetabolism adh adipose adiposityethnologyphysiology adna advance advances aerobiosis affymetrix afp africa african agencies agents agentspharmacologytherapeutic aging agingphysiology ai aids ajax alagenetics alanine alanine-scanning albida alcohol algorithm algorithms alignment alignmentinstrumentationmethods alignmentmethods alignmentmethodsstatistics alignmentstatistics alleles alligators allocation allosteric alternative aluka alzheimers ambiguity americana americans amino amsterdam amyloid anaerobiosis analysis analysismethods analysismethodsstatistics analysismethodstrends analysisstatistics anatomy ancestry ancient ancient_dna and aneuploidy angiosperms animal animals annotation anophelesgenetics ant_colony_systems anthozoa antibiotics antibody anticancer antigens antigenschemistrygenetics antimicrobial antineoplastic antisense antisensebiosynthesis antisensechemistry antisensegenetics antiviral api apoptosisphysiology arabidopsis arabidopsiscytologygeneticsmetabolism arabidopsisembryologygeneticsgrowth arabidopsisgenetics arabidopsisgeneticsgrowth arabidopsisgeneticsmetabolism arabidopsismetabolism araceae arbuscular archaea archaeal archaealgenetics arctic area arecaceae arlts1 array artficial_life arthropoda article artificial artificialchemistrygenetics artificialintelligence artificial_intelligence artificial_life artiodactyla assembly assessment association astral astrocytescytologydrug atlantic atp aulonemia automatedmethods automation aveneae aves azacitidineanalogs b bacillus bacteria bacterial bacterialanalysischemistry bacterialgenetics bacteriophage bacterium baker balance bamboos bananas banks barcoding barrel base base_composition based basilicum bats bayes bayesian bayesian_classifiers bd_simulation behavior benchmark benchmarkingstatistics beta-protein beta_sheet bhl bib bibtex-import bicoid binding bio biochemical biochemistry biodiversity biodiversityinformatics biodiversity_informatics biodiversity-informatics biofuels biogeography bioinf_methods bioinformatics biological biological-databases biology biologyhistory biologyinstrumentationmethods biologymethods biologymethodsstatistics biologystandardsstatistics biologystatistics biomass biometry biophysics biopython biosynthesis biotechnology biotinylation birding birds birth blast blastocystmetabolism blotting body bolivia book book2get boolean bootstrap botanyhistory bpti brainmetabolism brassica brazil brca1 brca2 breakagegenetics breast briza browse burkina bushes by c caenorhabditis caenorhabditisgenetics calibration california caloric cancer carboxylase career cargo_attachment carlo carnivora carrier caryopsis catalytic_mechanism cath cattle cd44genetics cdc42 cdf cdna ceareal celegans cell cell_cycle_inhibitors cells cellschemistrymetabolism cellscytologydrug cellsmetabolism cellsphysiology centromere centromerechemistrygenetics centromeregeneticsmetabolism century cereals cerebral cerevisiae cerevisiaedrug cerevisiaegenetics cerevisiaegeneticsmetabolism cgh chain chains change chaperones chaperonesmetabolism character characteristic chase checklist chemgenomics chemical cheminformatics chemistry chemoinformatics chenopodiaceae chenopodina chicken chickensgenetics chimp china chiroptera chloroplasts chromatin chromatinchemistry chromatingenetics chromatingeneticsmetabolism chromatingeneticsphysiology chromatinmetabolism chromatinmetabolismphysiology chromatinphysiology chromatinphysiologyradiation chromokinesin chromosomal chromosome chromosomes chromosomesgenetics chromosomesmetabolism chrysothamnus chusquea ciliary circadian cisplatin citation citizen cladistics class classification classifier clatex_3latexclatex_4latex cleaning cleansing cleft climate climatechange clinical clock cloning clupeaformis cluster clustering cnv co2 coa coalescent coarse_grain coarse-grained cockroach codegenetics codon codon_bias coevolution cognitive_maps coiled_coil cold coli coligenetics colimetabolism colinearity collaborate collective_computing collective_intelligence collective_systems combinatorial communication comparative comparative_genomics comparative_model comparative_modeling compensation competitive complementary complementarychemistry complementarygenetics complementarymetabolism complex complexes complexesmetabolism complexity complex_systems complicationsgenetics components composition compositiongenetics compositionphysiology computation computational computer computer-assisted computer_learning computers computer_science computing concept conductance conformation connectivity consensus conservation conserved constitution constrained constraint contact_maps contact_order contact_prediction contacts context contig continental contribution convergent_evolution cool cooperation copies copy core_genome coregonus core_residues core_structure correction correlated_motions correlated_mutations cortexcytologyembryologymetabolism cos cost costs countries cpg crocodiles crohns_disease crosses cross-linking cross-validation crystalization crystal_packing ctbp culicidaegenetics cultured curve cycle cyclicpharmacologytherapeutic cystic cytochrome cytoplasmic cytoplasmmetabolism cytosine-5--methyltransferasechemistrymetabolism cytosine-5--methyltransferasemetabolism cytosineanalysis cytoskeleton cytoskeletonmetabolism cytosolmetabolism daf-16 daf-2 damage damagegenetics danthoniodae darwin d-aspartate-l-isoaspartate data database databases datamining data_mining data-mining dataset ddm deacetylases debridement decision decision_trees decisiveness decsriptors dehydrogenase dehydrogenasegenetics dehydron delaunay deletion delta democracy demography denoising depsipeptides derek derivativespharmacologytherapeutic description descriptors desert design designing detection developed developing development developmental developmentaldrug developmentalgenetics developmentalgeneticsphysiology developmentgenetics developmentmetabolism developmentmetabolismpathology diagnosis diarrhena dictionary differentiation differentiationdrug diffraction digeorge digitisation diphosphate diploidy directed_evolution directional disassembly disassemblydrug disassemblygenetics disassemblygeneticsphysiology disassemblyphysiology disasters discovery discvovery disease diseases disorder dispersal distance_matrices distributed_computing distribution disulfide-bridges diterpenes divergence diversity divisionphysiology dna dna-binding dnachemistry dnachemistrygenetics dnachemistrymetabolism dnaclassificationgenetics dnacomputing dna-directed dnagenetics dnametabolism dnamethods dnamethodstrends dna_motor dnaphysiologyradiation dna_structure do docking _docking dogs dogsgenetics dolphins domain_motions domainsgenetics domain_swapping dosage dosagepharmacokinetics dose dose-response doublecortin double-strandedgeneticsmetabolism dransfield dransfieldia dream drosophila drosophilagenetics drug drug_design drug-discovery drupal dtc dunes duplicate duplication dworak dynamic dynamic_environments dynamic_optimization dynamic_programming dynamics dynein early ebook eclipse ecoinformatics ecological ecology ecosystem ecuador edge editing effect effects effectsenzymologygenetics effectsgenetics effectsgeneticsmetabolism effectsimmunology effectsmetabolism effectsphysiology eflora ef-tu eg5 electron electronicflora electrostatics elegans elegansgenetics elegansgeneticsmetabolism element elements elementsgenetics elymus em embryonic emergence encode encyclopedia endodeoxyribonucleaseschemistrymetabolism endometriosis energetics energy engineeringmethods enhancer enrichment entomolgy environment environmental enzyme eowilson epigenesis epigenetic epigenetics escherichia essential_genes est estimate estimation estradioladministration estrogen estrogenmetabolism estrogensmetabolism eucariotes eukaryote eukaryotic european eutrophication evaluation e-values evolution evolutionary_computation evolutionary-computation evolutionary_strategies exon exons exonsgenetics experimental explicit expressed expression extracts extramural extremevalue f1atpase factor factorgeneticsmetabolism factormetabolismpharmacology factors factorsanalysischemistry factorschemistry factorschemistrygenetics factorsdrug factorsgenetics factorsgeneticsmetabolism factorsgeneticsphysiology factorsmetabolism factorsphysiology factual factualtrends fad falciparumgenetics false familial family family_analysis familygenetics family-size faso fdh fdr feathers feeding female ferredoxin-reductase-fad-binding