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Group: baker-group - with tag protein_engineering [35 articles]

グループ baker-group のメンバーが最近追加した論文の一覧 with tag protein_engineering
  • Modest stabilization by most hydrogen-bonded side-chain interactions in membrane proteins
    Nature (25 May 2008)
    by Nathan H Joh, Andrew Min, Salem Faham, Julian P Whitelegge, Duan Yang, Virgil L Woods, James U Bowie
    posted to protein_engineering protein_folding structure by sobolevnrm to the group baker-group on 2008-07-24 12:12:58 as read
  • Kemp elimination catalysts by computational enzyme design
    Nature (19 March 2008)
    by Daniela Röthlisberger, Olga Khersonsky, Andrew M Wollacott, Lin Jiang, Jason Dechancie, Jamie Betker, Jasmine L Gallaher, Eric A Althoff, Alexandre Zanghellini, Orly Dym, Shira Albeck, Kendall N Houk, Dan S Tawfik, David Baker
    posted to protein_engineering structure_prediction by sobolevnrm to the group baker-group on 2008-06-27 12:04:48 as read along with 5 people jwm msuarezdiez austin cactus neils
  • From the Cover: Outer membrane protein G: Engineering a quiet pore for biosensing
    Proceedings of the National Academy of Sciences, Vol. 105, No. 17. (29 April 2008), pp. 6272-6277.
    by Min Chen, Syma Khalid, Mark S Sansom, Hagan Bayley
    posted to biomembranes ion_channels protein_engineering by sobolevnrm to the group baker-group on 2008-06-13 11:39:50 as read along with 1 person marck
  • Engineering Protein Allostery: 1.05 Å Resolution Structure and Enzymatic Properties of a Na+-activated Trypsin
    Journal of Molecular Biology, Vol. 378, No. 3. (2 May 2008), pp. 666-672.
    by Michael J Page, Christopher J Carrell, Enrico Di Cera
    posted to allostery protein_engineering protein-ligand_interactions thrombin by sobolevnrm to the group baker-group on 2008-05-03 12:32:51 as read
  • De Novo Computational Design of Retro-Aldol Enzymes
    Science, Vol. 319, No. 5868. (7 March 2008), pp. 1387-1391.
    by Lin Jiang, Eric A Althoff, Fernando R Clemente, Lindsey Doyle, Daniela Rothlisberger, Alexandre Zanghellini, Jasmine L Gallaher, Jamie L Betker, Fujie Tanaka, Carlos F Barbas, Donald Hilvert, Kendall N Houk, Barry L Stoddard, David Baker
    posted to protein_engineering by sobolevnrm to the group baker-group on 2008-04-18 11:13:25 as read along with 12 people and 2 groups barry aalibes jwm aprasad dgront zwang davidlott msuarezdiez scienbox ucbcjbm joseph_x_zhou cambray structural_bioinformatics McCammon
  • The Design and Evaluation of Heparin-Binding Foldamers
    Angewandte Chemie International Edition, Vol. 44, No. 41. (2005), pp. 6685-6689.
    by Sungwook Choi, Dylan J Clements, Vojislava Pophristic, Ivaylo Ivanov, Satyavani Vemparala, Joel S Bennett, Michael L Klein, Jeffrey D Winkler, William F Degrado
    posted to electrostatics protein_engineering protein_folding protein-ligand_interactions by sobolevnrm to the group baker-group on 2008-04-16 21:11:56 as read
  • Transitive homology-guided structural studies lead to discovery of Cro proteins with 40% sequence identity but different folds
    Proceedings of the National Academy of Sciences, Vol. 105, No. 7. (19 February 2008), pp. 2343-2348.
    by Christian G Roessler, Branwen M Hall, William J Anderson, Wendy M Ingram, Sue A Roberts, William R Montfort, Matthew H Cordes
    posted to bioinformatics protein_engineering structure by sobolevnrm to the group baker-group on 2008-03-13 11:41:42 as read along with 2 people barry cactus
  • Computational Design of Four-Helix Bundle Proteins That Bind Nonbiological Cofactors
    Biotechnol. Prog., Vol. 24, No. 1. (1 February 2008), pp. 74-79.
    by A Lehmann, JG Saven
    posted to protein_engineering by sobolevnrm to the group baker-group on 2008-02-19 12:32:26 as read
  • Designed Protein-Protein Association
    Science, Vol. 319, No. 5860. (11 January 2008), pp. 206-209.
    by Dirk Grueninger, Nora Treiber, Mathias O Ziegler, Jochen W Koetter, Monika-Sarah Schulze, Georg E Schulz
    posted to protein_engineering protein-protein_interactions by sobolevnrm to the group baker-group on 2008-02-18 12:21:23 as read along with 5 people cjeans zwang cactus biomcgary higueruelo
  • An improved pairwise decomposable finite-difference Poisson-Boltzmann method for computational protein design
    Journal of Computational Chemistry, Vol. 9999, No. 9999. (2007), NA.
    by Christina L Vizcarra, Naigong Zhang, Shannon A Marshall, Ned S Wingreen, Chen Zeng, Stephen L Mayo
    posted to electrostatics protein_engineering solvation by sobolevnrm to the group baker-group on 2008-01-21 12:56:17 as read
  • Modulating membrane protein stability and association by design
    Current Opinion in Structural Biology, Vol. In Press, Corrected Proof
    by Patrick Barth
    posted to biomembranes protein_engineering by sobolevnrm to the group baker-group on 2007-09-24 13:02:05 as read
  • Ligand binding and allostery can emerge simultaneously
    Protein Science, Vol. 16, No. 5. (2007), pp. 929-37.
    by J Liang, JR Kim, JT Boock, TJ Mansell, M Ostermeier
    posted to protein_engineering allostery by sobolevnrm to the group baker-group on 2007-05-25 14:37:08 as read
  • Electrostatics in computational protein design
    Current Opinion in Chemical Biology, Vol. 9, No. 6. (2005), pp. 622-6.
    by CL Vizcarra, SL Mayo
    posted to protein_engineering electrostatics by sobolevnrm to the group baker-group on 2007-05-25 14:37:06 as read
  • Establishing the entatic state in folding metallated Pseudomonas aeruginosa azurin
    Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, No. 9. (2007), pp. 3159-64.
    by C Zong, CJ Wilson, T Shen, Wittung P Stafshede, SL Mayo, PG Wolynes
    posted to protein_folding protein_engineering metalloregulation allostery by sobolevnrm to the group baker-group on 2007-05-25 14:36:48 as read
  • Redesigning protein pKa values
    Protein Science, Vol. 16, No. 2. (2007), pp. 239-49.
    by Tynan BM Connolly, JE Nielsen
    posted to solvation protein_engineering pka electrostatics by sobolevnrm to the group baker-group on 2007-05-25 14:36:04 as read
  • Simple electrostatic model improves designed protein sequences
    Protein Science, Vol. 15, No. 8. (2006), pp. 2014-8.
    by ES Zollars, SA Marshall, SL Mayo
    posted to protein_engineering electrostatics by sobolevnrm to the group baker-group on 2007-05-25 14:23:17 as read
  • Computational redesign of endonuclease DNA binding and cleavage specificity
    Nature, Vol. 441, No. 7093. (2006), pp. 656-9.
    by J Ashworth, JJ Havranek, CM Duarte, D Sussman, Jr, BL Stoddard, D Baker
    posted to protein_engineering protein-nucleic_acid_interactions nucleic_acids by sobolevnrm to the group baker-group on 2007-05-25 14:22:46 as read
  • Structural Studies of an Engineered Zinc Biosensor Reveal an Unanticipated Mode of Zinc Binding
    Journal of Molecular Biology, Vol. 354, No. 4. (2005), pp. 829-40.
    by PG Telmer, BH Shilton
    posted to protein_engineering metalloregulation by sobolevnrm to the group baker-group on 2007-05-25 14:19:26 as read
  • Thrombin inhibitors identified by computer-assisted multiparameter design
    Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, No. 24. (2005), pp. 8597-602.
    by D Riester, F Wirsching, G Salinas, M Keller, M Gebinoga, S Kamphausen, C Merkwirth, R Goetz, M Wiesenfeldt, J Stã¼rzebecher, W Bode, R Friedrich, M Thã¼rk, A Schwienhorst
    posted to thrombin protein_engineering protein-ligand_interactions by sobolevnrm to the group baker-group on 2007-05-25 14:17:41 as read
  • Engineering of protease variants exhibiting high catalytic activity and exquisite substrate selectivity
    Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, No. 19. (2005), pp. 6855-60.
    by N Varadarajan, J Gam, MJ Olsen, G Georgiou, BL Iverson
    posted to thrombin protein_engineering by sobolevnrm to the group baker-group on 2007-05-25 14:17:41 as read
  • Artificial Allosteric Control of Maltose Binding Protein
    Physical Review Letters, Vol. 94 (2005)
    by B Choi, G Zocchi, S Canale, Y Wu, S Chan, LJ Perry
    posted to protein_engineering allostery by sobolevnrm to the group baker-group on 2007-05-25 14:15:42 as read
  • Recapitulation of Protein Family Divergence using Flexible Backbone Protein Design
    Journal of Molecular Biology, Vol. 346, No. 2. (2005), pp. 631-44.
    by CT Saunders, D Baker
    posted to protein_engineering by sobolevnrm to the group baker-group on 2007-05-25 14:15:19 as read
  • Thermodynamic prediction of protein neutrality
    Proceedings of the National Academy of Sciences of the United States of America, Vol. 102, No. 3. (2005), pp. 606-11.
    by JD Bloom, JJ Silberg, CO Wilke, DA Drummond, C Adami, FH Arnold
    posted to protein_engineering bioinformatics by sobolevnrm to the group baker-group on 2007-05-25 14:15:19 as read
  • Advances in computational protein design
    Current Opinion in Structural Biology, Vol. 14, No. 4. (2004), pp. 487-94.
    by S Park, X Yang, JG Saven
    posted to protein_engineering by sobolevnrm to the group baker-group on 2007-05-25 14:15:19 as read
  • Optimising enzyme function by directed evolution
    Current Opinion in Structural Biology, Vol. 13, No. 4. (2003), pp. 500-5.
    by PA Dalby
    posted to protein_engineering by sobolevnrm to the group baker-group on 2007-05-25 14:15:19 as read
  • Designing redox metalloproteins from bottom-up and top-down perspectives
    Current Opinion in Structural Biology, Vol. 13, No. 4. (2003), pp. 490-9.
    by PD Barker
    posted to protein_engineering by sobolevnrm to the group baker-group on 2007-05-25 14:15:19 as read
  • Computational design of receptor and sensor proteins with novel functions
    Nature, Vol. 423, No. 6936. (2003), pp. 185-90.
    by LL Looger, MA Dwyer, JJ Smith, HW Hellinga
    posted to protein_engineering by sobolevnrm to the group baker-group on 2007-05-25 14:15:19 as read
  • Designing proteins for therapeutic applications
    Current Opinion in Structural Biology, Vol. 13, No. 4. (2003), pp. 513-8.
    by G Lazar, SA Marshall, JJ Plecs, SL Mayo, JR Desjarlais
    posted to protein_engineering by sobolevnrm to the group baker-group on 2007-05-25 14:15:19 as read
  • Periplasmic binding proteins: a versatile superfamily for protein engineering
    Current Opinion in Structural Biology, Vol. 14, No. 4. (2004), pp. 495-504.
    by MA Dwyer, HW Hellinga
    posted to protein_engineering by sobolevnrm to the group baker-group on 2007-05-25 14:15:19 as read
  • Glu-192 --> Gln Substitution in Thrombin Mimics the Catalytic Switch Induced by Thrombomodulin
    Proceedings of the National Academy of Sciences of the United States of America, Vol. 88, No. 16. (1991), pp. 7371-5.
    by BFL Bonniec, CT Esmon
    posted to thrombin protein_engineering by sobolevnrm to the group baker-group on 2007-05-25 14:15:19 as read
  • Converting Trypsin to Chymotrypsin: The Role of Surface Loops
    Science, Vol. 255, No. 5049. (1992), pp. 1249-53.
    by L Hedstrom, L Szilagyi, WJ Rutter
    posted to thrombin protein_engineering by sobolevnrm to the group baker-group on 2007-05-25 14:15:06 as read
  • Redesigning Trypsin: Alteration of Substrate Specificity
    Science, Vol. 228, No. 4697. (1985), pp. 291-7.
    by CS Craik, C Largman, T Fletcher, S Roczniak, PJ Barr, R Fletterick, WJ Rutter
    posted to thrombin protein_engineering by sobolevnrm to the group baker-group on 2007-05-25 14:15:06 as read
  • Rational engineering of activity and specificity in a serine protease
    Nature Biotechnology, Vol. 15, No. 2. (1997), pp. 146-9.
    by QD Dang, ER Guinto, E Di Cera
    posted to thrombin protein_engineering by sobolevnrm to the group baker-group on 2007-05-25 14:15:06 as read
  • Computational Design of a Biologically Active Enzyme
    Science, Vol. 304, No. 5679. (2004), pp. 1967-71.
    by MA Dwyer, LL Looger, HW Hellinga
    posted to protein_folding protein_engineering by sobolevnrm to the group baker-group on 2007-05-25 14:10:46 as read
  • Creation of an allosteric enzyme by domain insertion
    Journal of Molecular Biology, Vol. 336, No. 1. (2004), pp. 263-273.
    by G Guntas, M Ostermeier
    posted to protein_engineering allostery by sobolevnrm to the group baker-group on 2007-05-25 14:01:51 as read
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