A brief history of RNAi: the silence of the genes.

@article{citeulike:779072, abstract = {The use of the RNA interference (RNAi) pathway to eliminate gene products has greatly facilitated the understanding of gene function. Behind this remarkable pathway is an intricate network of proteins that ensures the degradation of the target mRNA. In this review, we explore the history of RNAi as well as highlighting recent discoveries.}, address = {Department of Molecular Pharmacology, Baxter Laboratory in Genetic Pharmacology, 269 Campus Dr., CCSR 4225A, Stanford University School of Medicine, Stanford, California 94305, USA. gsen@stanford.edu}, author = {Sen, G. L. and Blau, H. M. }, citeulike-article-id = {779072}, doi = {http://dx.doi.org/10.1096/fj.06-6014rev}, issn = {1530-6860}, journal = {FASEB J}, keywords = {review, rnai, rnainterference}, month = {July}, number = {9}, pages = {1293--1299}, posted-at = {2007-04-12 20:15:35}, priority = {4}, title = {A brief history of RNAi: the silence of the genes.}, url = {http://dx.doi.org/10.1096/fj.06-6014rev}, volume = {20}, year = {2006} }

TY - JOUR ID - citeulike:779072 L3 - citeulike-article-id:779072 TI - A brief history of RNAi: the silence of the genes. JF - FASEB J VL - 20 IS - 9 SP - 1293 EP - 1299 AD - Department of Molecular Pharmacology, Baxter Laboratory in Genetic Pharmacology, 269 Campus Dr., CCSR 4225A, Stanford University School of Medicine, Stanford, California 94305, USA. gsen@stanford.edu SN - 1530-6860 N2 - The use of the RNA interference (RNAi) pathway to eliminate gene products has greatly facilitated the understanding of gene function. Behind this remarkable pathway is an intricate network of proteins that ensures the degradation of the target mRNA. In this review, we explore the history of RNAi as well as highlighting recent discoveries. KW - review KW - rnai KW - rnainterference AU - Sen, GL AU - Blau, HM PY - 2006/07// UR - http://dx.doi.org/10.1096/fj.06-6014rev ER -